There are 8 main types of blood separated into 4 groups. The groups are A, B, AB, and O. They are grouped together by the presence or absence of what is known as an antigen. Antigens are substances within the blood that cause our immune systems to create antibodies. These antibodies then kill anything the immune system thinks is a threat. The specific antigens that create the different blood types are found on the surface of red blood cells and are known as type A and type B. They’re further separated by the presence of another type of antigen known as rH factor. If you have this rH antigen present, you’re considered positive, if not, you’re considered negative. Someone that has type A antigens and rH factor is considered to have type A+ blood. If you have both types of antigens and no rH factor, you have type AB- blood. If you have no A or B antigens then you are type O blood.
All of this matters because of those antibodies your immune system creates. Someone with type A blood will have antibodies for type B, and someone with type B will have antibodies for type A. Type O has antibodies for both A and B. If you were to give type B blood to someone who was type A, their antibodies would attack the type A red blood cells causing very unwanted side effects, including possible death!